Rnf181
WebJun 1, 2001 · Directly interacts with ITGA2B and, as a result, with integrin ITGA2B/ITGB3. There is no evidence that integrin ITGA2B/ITGB3 is an endogenous substrate for RNF181-directed ubiquitination. By similarity WebPrimePCR™ Template for SYBR® Green Assay: Rnf181, Rat Reaction: 4 billion copies/200 µl desalted Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.
Rnf181
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WebRNF181 is also expressed in platelets (at protein level). Description. RNF181 Human Recombinant produced in E. coli is a single polypeptide chain containing 176 amino acids (1-153) and having a molecular mass of 20.3 kDa. RNF181 is fused to a 23 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques. WebSep 1, 2011 · Negative Regulation of CARD11 Signaling and Lymphoma Cell Survival by the E3 Ubiquitin Ligase RNF181. 11: 18331836: 2008: RN181, a novel ubiquitin E3 ligase that interacts with the KVGFFKR motif of platelet integrin alpha(IIb)beta3. 9: 30714150: 2024: RN181 is a tumour suppressor in gastric cancer by regulation of the ERK/MAPK-cyclin …
WebHuman diseases caused by Rnf181 mutations. The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in … WebRNF181 INFORMATION. Proteini. Full gene name according to HGNC. Ring finger protein 181. Gene namei. Official gene symbol, which is typically a short form of the gene name, …
WebThe expression of RNF181 is correlated with ERα level in human breast tumors and relates to poor survival in endocrine-treated patients. RNF181 depletion inhibits breast cancer … WebRNF181 binds the integrin alpha-IIb (ITGA2B)/beta-3 (ITGB3) complex and has E3 ubiquitin ligase activity (Brophy et al., 2008). ⚠WARNING: This product can expose you to …
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WebJul 6, 2024 · RNF181 could be an interesting marker for triple negative breast cancer prognostics and therapeutics. Breast cancer ranks No. 1 in women cancer incidence, … climate shield cs2 rain screen clipWebRNF181 is also expressed in platelets (at protein level). Description. RNF181 Human Recombinant produced in E. coli is a single polypeptide chain containing 176 amino acids … climate shield ipeWebGene ID: 127289571, updated on 31-Oct-2024. Summary Other designations. E3 ubiquitin-protein ligase RNF181-like boat vinyl graphicsWebGene ID: 126495266, updated on 3-Mar-2024. Summary Other designations. E3 ubiquitin-protein ligase RNF181 climate shield hvacWebThe 153-amino acid protein contains a RING finger domain. RT-PCR analysis detected highest levels of expression in liver and heart, moderate levels in placenta, lung, liver, kidney, pancreas, and lower levels in brain and skeletal muscle. Western blot analysis detected RNF181 protein in human platelets as a 36-kD dimer and an 18-kD monomer. climate shedsWebJul 6, 2024 · RNF181 depletion decreased YAP protein level and Hippo signaling target genes, such as CTGF and CYR61, in TNBC cell lines. Immuno-precipitation assay showed … climate shield coversWebSep 24, 2024 · RNF181 interacts with ERα protein, stabilizes ERα and facilitates its signaling activation and breast cancer progression. The importance of ERα signaling in the … boat vinyl flooring material